On the Estimation of Total Arterial Compliance from Aortic Pulse Wave Velocity

Optimized Estimation of Global and Regional Aortic Pulse Wave Velocity

Introduction: Pulse wave velocity (PWV) as a measure of aortic stiffness is an important clinical marker for the presence of atherosclerosis [1,2]. For PWV estimation using Phase contrast (PC) MRI transit-time (TT) methods have been employed which estimate temporal differences in flow waveforms between two locations in the vessel with known distance [3]. However, precision was limited by the ac...

Determination of aortic pulse wave velocity from waveform decomposition of the central aortic pressure pulse.

Aortic pulse wave velocity (PWV), calculated from pulse transit time (PTT) using 2 separate pulse recordings over a known distance, is a significant biomarker of cardiovascular risk. This study evaluates a novel method of determining PTT from waveform decomposition of central aortic pressure using a single pulse measurement. Aortic pressure was estimated from a transformed radial pulse and deco...

Smooth muscle relaxation: effects on arterial compliance, distensibility, elastic modulus, and pulse wave velocity.

Compliance, distensibility, incremental elastic modulus (E(inc)), and pulse wave velocity are all terms used to describe the mechanical properties of arteries. Previous studies assessing the effects of smooth muscle relaxation on each of these parameters have produced conflicting results. Our laboratory has previously demonstrated that intrabrachial infusion of nitroglycerin in normal human sub...

Effects on Arterial Compliance, Distensibility, Elastic Modulus, and Pulse Wave Velocity

Compliance, distensibility, incremental elastic modulus (Einc), and pulse wave velocity are all terms used to describe the mechanical properties of arteries. Previous studies assessing the effects of smooth muscle relaxation on each of these parameters have produced conflicting results. Our laboratory has previously demonstrated that intrabrachial infusion of nitroglycerin in normal human subje...

Arterial pulse wave velocity and heart rate.